LMy Longevity Picks

AgelessRx vs Willow: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

AgelessRx wins overall, scoring 7.7/10 vs 6.5/10. Mainly on what they can prescribe and real monthly cost.

Our pick: AgelessRx

AgelessRx wins overall, scoring 7.7/10 vs 6.5/10.

Winner
#6 of 31

AgelessRx

7.7

A Michigan longevity telehealth service with a named medical director and the rare combination of NAD+, rapamycin with lab work included, metformin and low dose naltrexone on one menu.

from $149/mo on a 3-month plan billed in full, after a $79 first month

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#21 of 31

WillowWillow

6.5

Names its company, 36 physicians and five pharmacies, but not the dose its $199 NAD+ vial contains or which pharmacy makes it.

from $199/mo billed monthly until cancelled

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AgelessRx vs Willow, side by side

FeatureAgelessRxWillow
Our score7.7/106.5/10
Starting price$149/mo on a 3-month plan billed in full, after a $79 first month$199/mo billed monthly until cancelled
Medication typesmetformin, nad-injection, nad-nasal-spray, rapamycinnad-injection
Best for——
Overall ranking#6#21
Real monthly cost (25%)7.56.0
Prescriber & follow-up (30%)7.57.5
What they can prescribe (20%)8.55.5
What they disclose (25%)7.56.5

Sources: AgelessRx pricing verified on agelessrx.com, Willow pricing verified on startwillow.com

Pros & cons

AgelessRx

Pros

  • + Rapamycin at $65/month with "Baseline and ongoing blood work included"
  • + NAD+ injection from $79/mo on a 3-month plan; nasal spray also offered
  • + Names its CEO, Anar Isman, and its Medical Director, Dr. Jenell Decker, MD, with a published Ann Arbor address

Cons

  • − Weaker on Real monthly cost (7.5/10)
  • − Weaker on Prescriber & follow-up (7.5/10)
  • − Weaker on What they disclose (7.5/10)

Willow

Pros

  • + Names its legal entity with a street address, 36 US-licensed physicians with individual bio pages, and all five partner pharmacies with full addresses
  • + One published monthly price that states what it includes: the vial, syringes, needles, doctor access and free shipping
  • + States plainly that compounded NAD+ is not FDA-approved, on the product page and its safety page

Cons

  • − Weaker on What they can prescribe (5.5/10)
  • − Weaker on Real monthly cost (6.0/10)
  • − Weaker on What they disclose (6.5/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), AgelessRx (7.7/10) comes out ahead of Willow (6.5/10). But the right choice still depends on what matters most to you.

Choose AgelessRx if you want this option. From $149/mo on a 3-month plan billed in full, after a $79 first month.

Read Review →

Choose Willow if you want this option. From $199/mo billed monthly until cancelled.

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Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is AgelessRx.

AgelessRxRead Review
Willow · from $199/mo billed monthly until cancelledVisit →
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Frequently asked questions

Which is better, AgelessRx or Willow?
AgelessRx scores higher overall (7.7/10 vs 6.5/10) and is our recommended pick for most people. AgelessRx also has the lower starting price at $149/mo on a 3-month plan billed in full, after a $79 first month.
How much does AgelessRx cost vs Willow?
AgelessRx is from $149/mo on a 3-month plan billed in full, after a $79 first month and Willow is from $199/mo billed monthly until cancelled. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between AgelessRx and Willow?
AgelessRx (7.7/10, #6 of 31) and Willow (6.5/10, #21 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does AgelessRx or Willow take insurance?
Neither AgelessRx nor Willow typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs AgelessRx→HealthRX vs Willow→MadeMed vs AgelessRx→MadeMed vs Willow→Ivy Rx vs AgelessRx→Ivy Rx vs Willow→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.