LMy Longevity Picks

He & She MD vs Hone Health: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

He & She MD wins overall, scoring 6.8/10 vs 6.4/10. Mainly on what they can prescribe and real monthly cost. If price is your priority, Hone Health is cheaper at $175/mo plus a membership ($25 or $155/mo).

Our pick: He & She MD

He & She MD wins overall, scoring 6.8/10 vs 6.4/10. If price is your priority, Hone Health is cheaper at $175/mo plus a membership ($25 or $155/mo).

Winner
#19 of 31

He & She MDHe & She MD

6.8

Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.

from $229/mo on a monthly plan ($139/mo on the annual plan)

Read Review
#24 of 31

Hone HealthHone Health

6.4

A 1:1 physician video consult and a 50+ biomarker panel, with the price split across medication, membership and a lab fee.

from $175/mo plus a membership ($25 or $155/mo)

Read Review

He & She MD vs Hone Health, side by side

FeatureHe & She MDHone Health
Our score6.8/106.4/10
Starting price$229/mo on a monthly plan ($139/mo on the annual plan)$175/mo plus a membership ($25 or $155/mo)
Medication typesnad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-creamsermorelin-injection, bloodwork
Best for—Best for clinical oversight
Overall ranking#19#24
Real monthly cost (25%)7.0Not scored (5.0)
Prescriber & follow-up (30%)6.08.0
What they can prescribe (20%)8.55.0
What they disclose (25%)6.07.0

Sources: He & She MD pricing verified on heandshemd.com, Hone Health pricing verified on honehealth.com

Pros & cons

He & She MD

Pros

  • + Full commitment ladder published before intake, all four tiers
  • + NAD+ dose published (1000 mg)
  • + Six longevity products across injection, cream and nasal spray

Cons

  • − Weaker on Prescriber & follow-up (6.0/10)
  • − Weaker on What they disclose (6.0/10)
  • − Weaker on Real monthly cost (7.0/10)

Hone Health

Pros

  • + Private 1:1 video consultation with a board-certified physician
  • + 50+ biomarker panel, testable at over 2,000 lab locations
  • + No commitments, cancel anytime, with the full legal set published

Cons

  • − Weaker on Real monthly cost (5.0/10)
  • − Weaker on What they can prescribe (5.0/10)
  • − Weaker on What they disclose (7.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), He & She MD (6.8/10) comes out ahead of Hone Health (6.4/10). But the right choice still depends on what matters most to you.

Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).

Read Review →

Choose Hone Health if you want best for clinical oversight. From $175/mo plus a membership ($25 or $155/mo).

Read Review →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is He & She MD.

Frequently asked questions

Which is better, He & She MD or Hone Health?
He & She MD scores higher overall (6.8/10 vs 6.4/10) and is our recommended pick for most people. If price is the priority, Hone Health starts at $175/mo plus a membership ($25 or $155/mo).
How much does He & She MD cost vs Hone Health?
He & She MD is from $229/mo on a monthly plan ($139/mo on the annual plan) and Hone Health is from $175/mo plus a membership ($25 or $155/mo). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between He & She MD and Hone Health?
He & She MD (6.8/10, #19 of 31) and Hone Health (6.4/10, #24 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does He & She MD or Hone Health take insurance?
Neither He & She MD nor Hone Health typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs He & She MD→HealthRX vs Hone Health→MadeMed vs He & She MD→MadeMed vs Hone Health→Ivy Rx vs He & She MD→Ivy Rx vs Hone Health→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

One of these earns us a commission if you sign up. Scores are unaffected; partners are listed first at equal displayed scores. How this works →

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.