MadeMed vs He & She MD: Which longevity Clinic Is Better in 2026?
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Short answer
MadeMed wins overall, scoring 8.2/10 vs 6.8/10. Mainly on prescriber & follow-up and what they disclose.
Ties the dose to a lab value, and names the marker it uses.
from $169/mo on a 6-month plan billed $1,014
Read Review
He & She MD
Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.
from $229/mo on a monthly plan ($139/mo on the annual plan)
Read ReviewMadeMed vs He & She MD, side by side
| Feature | MadeMed | He & She MD |
|---|---|---|
| Our score | 8.2/10 | 6.8/10 |
| Starting price | $169/mo on a 6-month plan billed $1,014 | $229/mo on a monthly plan ($139/mo on the annual plan) |
| Medication types | sermorelin-injection, sermorelin-oral, nad-injection, nad-nasal-spray, peptides | nad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream |
| Best for | Best for clinical specificity | — |
| Overall ranking | #2 | #19 |
| Real monthly cost (25%) | 8.0 | 7.0 |
| Prescriber & follow-up (30%) | 8.5 | 6.0 |
| What they can prescribe (20%) | 8.0 | 8.5 |
| What they disclose (25%) | 8.0 | 6.0 |
Sources: MadeMed pricing verified on mademed.com, He & She MD pricing verified on heandshemd.com
Pros & cons
MadeMed
Pros
- + Board-certified physician consultation included in the price
- + Requires a lab test before prescribing, and doses sermorelin against your IGF-1
- + States the dose on every product. 9mg/3mL daily, NAD+ 1000mg across 8 injections a month
Cons
- − Weaker on Real monthly cost (8.0/10)
- − Weaker on What they can prescribe (8.0/10)
- − Weaker on What they disclose (8.0/10)
He & She MD
Pros
- + Full commitment ladder published before intake, all four tiers
- + NAD+ dose published (1000 mg)
- + Six longevity products across injection, cream and nasal spray
Cons
- − Weaker on Prescriber & follow-up (6.0/10)
- − Weaker on What they disclose (6.0/10)
- − Weaker on Real monthly cost (7.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), MadeMed (8.2/10) comes out ahead of He & She MD (6.8/10). But the right choice still depends on what matters most to you.
Choose MadeMed if you want best for clinical specificity. From $169/mo on a 6-month plan billed $1,014.
Read Review →Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).
Read Review →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is MadeMed.
Frequently asked questions
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.