LMy Longevity Picks

He & She MD vs YourEra: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

He & She MD and YourEra tie at 6.8/10, so it comes down to price and what they can prescribe and prescriber & follow-up. YourEra is cheaper at $170/mo with no long-term contract, cancel anytime.

Nearly tied: He & She MD vs YourEra

He & She MD and YourEra are essentially tied, 6.8/10 vs 6.7/10. If price is your priority, YourEra is cheaper at $170/mo with no long-term contract, cancel anytime.

Winner
#19 of 31

He & She MDHe & She MD

6.8

Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.

from $229/mo on a monthly plan ($139/mo on the annual plan)

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#20 of 31

YourEra

6.7

LegitScript-certified, and its affiliate link lands on a page that never mentions NAD+, the product we ranked it for.

from $170/mo with no long-term contract, cancel anytime

Visit →

He & She MD vs YourEra, side by side

FeatureHe & She MDYourEra
Our score6.8/106.7/10
Starting price$229/mo on a monthly plan ($139/mo on the annual plan)$170/mo with no long-term contract, cancel anytime
Medication typesnad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-creamnad-injection
Best for——
Overall ranking#19#20
Real monthly cost (25%)7.07.0
Prescriber & follow-up (30%)6.07.0
What they can prescribe (20%)8.55.5
What they disclose (25%)6.07.0

Sources: He & She MD pricing verified on heandshemd.com, YourEra pricing verified on yourera.com

Pros & cons

He & She MD

Pros

  • + Full commitment ladder published before intake, all four tiers
  • + NAD+ dose published (1000 mg)
  • + Six longevity products across injection, cream and nasal spray

Cons

  • − Weaker on Prescriber & follow-up (6.0/10)
  • − Weaker on What they disclose (6.0/10)
  • − Weaker on Real monthly cost (7.0/10)

YourEra

Pros

  • + Flat pricing stated outright. Same price at every dose, visit and shipping included
  • + LegitScript-certified, with the public listing on legitscript.com linked from the site
  • + Compounded-drug FDA disclosure published in its own words, not buried

Cons

  • − Weaker on What they can prescribe (5.5/10)
  • − Weaker on Real monthly cost (7.0/10)
  • − Weaker on Prescriber & follow-up (7.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), He & She MD and YourEra are essentially tied (6.8 vs 6.7/10). There is no clear overall winner here, so the right choice comes down to what matters most to you.

Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).

Read Review →

Choose YourEra if you want this option. From $170/mo with no long-term contract, cancel anytime.

Visit →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

He & She MD and YourEra are essentially tied. Either is a solid choice.

He & She MDRead Review
YourEra · from $170/mo with no long-term contract, cancel anytimeVisit →
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Frequently asked questions

Which is better, He & She MD or YourEra?
He & She MD and YourEra are essentially tied (6.8/10 vs 6.7/10). There's no clear overall winner. If price is the deciding factor, YourEra starts at $170/mo with no long-term contract, cancel anytime.
How much does He & She MD cost vs YourEra?
He & She MD is from $229/mo on a monthly plan ($139/mo on the annual plan) and YourEra is from $170/mo with no long-term contract, cancel anytime. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between He & She MD and YourEra?
He & She MD (6.8/10, #19 of 31) and YourEra (6.7/10, #20 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does He & She MD or YourEra take insurance?
Neither He & She MD nor YourEra typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs He & She MD→HealthRX vs YourEra→MadeMed vs He & She MD→MadeMed vs YourEra→Ivy Rx vs He & She MD→Ivy Rx vs YourEra→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.