LMy Longevity Picks

He & She MD vs YourEra: Which longevity Clinic Is Better in 2026?

21 clinics scoredPrices checked weekly0 paid rankings

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Short answer

He & She MD and YourEra tie at 6.8/10, so it comes down to price and what they can prescribe and prescriber & follow-up. YourEra is cheaper at $170/mo.

Nearly tied: He & She MD vs YourEra

He & She MD and YourEra are essentially tied, 6.8/10 vs 6.7/10. If price is your priority, YourEra is cheaper at $170/mo.

Winner
#12 of 21

He & She MD

6.8

Publishes the whole ladder and the dose — then quotes a different annual price on its own two longevity pages.

from $229/mo

Visit He & She MD
#13 of 21

YourEra

6.7

The only clinic here with a LegitScript certification, and the only one whose affiliate link never mentions the product we ranked it for.

from $170/mo

Visit YourEra

He & She MD vs YourEra, side by side

FeatureHe & She MDYourEra
Our score6.8/106.7/10
Starting price$229/mo$170/mo
Medication typesnad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-creamnad-injection
Best for
Overall ranking#12#13
Real monthly cost (25%)7.07.0
Prescriber & follow-up (30%)6.07.0
What they can prescribe (20%)8.55.5
What they disclose (25%)6.07.0

Sources: He & She MD pricing verified on heandshemd.com, YourEra pricing verified on yourera.com

Pros & cons

He & She MD

Pros

  • + Full commitment ladder published before intake, all four tiers
  • + NAD+ dose published (1000 mg), which most of this set does not
  • + Six longevity products across injection, cream and nasal spray

Cons

  • Weaker on Prescriber & follow-up (6.0/10)
  • Weaker on What they disclose (6.0/10)
  • Weaker on Real monthly cost (7.0/10)

YourEra

Pros

  • + Flat pricing stated outright — same price at every dose, visit and shipping included
  • + LegitScript-certified, an external check no other clinic in this set carries
  • + Compounded-drug FDA disclosure published in its own words, not buried

Cons

  • Weaker on What they can prescribe (5.5/10)
  • Weaker on Real monthly cost (7.0/10)
  • Weaker on Prescriber & follow-up (7.0/10)

The bottom line

After scoring all 21 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), He & She MD and YourEra are essentially tied (6.8 vs 6.7/10) — there is no clear overall winner here, so the right choice comes down to what matters most to you.

Choose He & She MD if you want this optionfrom $229/mo.

Visit He & She MD

Choose YourEra if you want this optionfrom $170/mo.

Visit YourEra

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →

Ready to start longevity care?

He & She MD and YourEra are essentially tied — either is a solid choice.

Frequently asked questions

Which is better, He & She MD or YourEra?
He & She MD and YourEra are essentially tied (6.8/10 vs 6.7/10) — there's no clear overall winner. If price is the deciding factor, YourEra starts at $170/mo.
How much does He & She MD cost vs YourEra?
He & She MD is from $229/mo and YourEra is from $170/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between He & She MD and YourEra?
He & She MD (6.8/10, #12 of 21) and YourEra (6.7/10, #13 of 21) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does He & She MD or YourEra take insurance?
Neither He & She MD nor YourEra typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs He & She MDHealthRX vs YourEraMadeMed vs He & She MDMadeMed vs YourEraPallas Health vs He & She MDPallas Health vs YourEra
Ranked by score

Top picks

HealthRXfrom $161/mo

Best for published pricing

Paid link · ranks 1 of 21 on our methodology either way
Go to HealthRXRead review
MadeMedfrom $169/mo

Best for clinical specificity

Ranks 2 of 21 · no commercial relationship
Read the MadeMed review
Pallas Healthfrom $189/mo

Best for explaining the category

Paid link · ranks 3 of 21 on our methodology either way
Go to Pallas HealthRead review

2 of these earn us a commission if you sign up. Scores and rank are unaffected. How this works →

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.

Top Pick · $161/mo

HealthRX

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$161/mo is a real, ongoing rate on the plan it applies to — our evidence shows no sign it's a promotional rate that rises later.