Hone Health vs RxSpan MD: Which longevity Clinic Is Better in 2026?
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Short answer
Hone Health wins overall, scoring 6.4/10 vs 6.1/10. Mainly on what they can prescribe and prescriber & follow-up. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).
Hone Health wins overall, scoring 6.4/10 vs 6.1/10. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).
Hone Health
A 1:1 physician video consult and a 50+ biomarker panel, with the price split across medication, membership and a lab fee.
from $175/mo plus a membership ($25 or $155/mo)
Read Review
Eight longevity treatments priced, and not one ongoing price.
from $150/mo on a prepaid 12-month plan ($249 month to month)
Visit →Hone Health vs RxSpan MD, side by side
| Feature | Hone Health | RxSpan MD |
|---|---|---|
| Our score | 6.4/10 | 6.1/10 |
| Starting price | $175/mo plus a membership ($25 or $155/mo) | $150/mo on a prepaid 12-month plan ($249 month to month) |
| Medication types | sermorelin-injection, bloodwork | nad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue |
| Best for | Best for clinical oversight | — |
| Overall ranking | #24 | #26 |
| Real monthly cost (25%) | Not scored (5.0) | 6.0 |
| Prescriber & follow-up (30%) | 8.0 | 5.5 |
| What they can prescribe (20%) | 5.0 | 8.5 |
| What they disclose (25%) | 7.0 | 5.0 |
Sources: Hone Health pricing verified on honehealth.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
Hone Health
Pros
- + Private 1:1 video consultation with a board-certified physician
- + 50+ biomarker panel, testable at over 2,000 lab locations
- + No commitments, cancel anytime, with the full legal set published
Cons
- − Weaker on Real monthly cost (5.0/10)
- − Weaker on What they can prescribe (5.0/10)
- − Weaker on What they disclose (7.0/10)
RxSpan MD
Pros
- + Eight longevity treatments, each with a figure attached
- + Price is stated to include consult, medication, supplies, shipping and support
- + Says plainly that a prescription is not guaranteed
Cons
- − Weaker on What they disclose (5.0/10)
- − Weaker on Prescriber & follow-up (5.5/10)
- − Weaker on Real monthly cost (6.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Hone Health (6.4/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.
Choose Hone Health if you want best for clinical oversight. From $175/mo plus a membership ($25 or $155/mo).
Read Review →Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).
Visit →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is Hone Health.
Frequently asked questions
Which is better, Hone Health or RxSpan MD?
How much does Hone Health cost vs RxSpan MD?
What is the difference between Hone Health and RxSpan MD?
Does Hone Health or RxSpan MD take insurance?
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.