Hone Health vs RxSpan MD: Which longevity Clinic Is Better in 2026?
Summarize this page with
Short answer
Hone Health wins overall, scoring 6.4/10 vs 6.0/10 — mainly on what they can prescribe and prescriber & follow-up. If price is your priority, RxSpan MD is cheaper at $149/mo.
Hone Health wins overall, scoring 6.4/10 vs 6.0/10. If price is your priority, RxSpan MD is cheaper at $149/mo.
Hone Health
The most thorough clinical workup here, and the least comparable price.
from $175/mo
Visit Hone HealthRxSpan MD
The widest longevity menu here, and not one ongoing price.
from $149/mo
Visit RxSpan MDHone Health vs RxSpan MD, side by side
| Feature | Hone Health | RxSpan MD |
|---|---|---|
| Our score | 6.4/10 | 6.0/10 |
| Starting price | $175/mo | $149/mo |
| Medication types | sermorelin-injection, bloodwork | nad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue |
| Best for | Best for clinical oversight | — |
| Overall ranking | #8 | #10 |
| Real monthly cost (25%) | 5.0 | 5.5 |
| Prescriber & follow-up (30%) | 8.0 | 5.5 |
| What they can prescribe (20%) | 5.0 | 8.5 |
| What they disclose (25%) | 7.0 | 5.0 |
Sources: Hone Health pricing verified on honehealth.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
Hone Health
Pros
- + Private 1:1 video consultation with a board-certified physician
- + 50+ biomarker panel, testable at over 2,000 lab locations
- + No commitments, cancel anytime, with the full legal set published
Cons
- − Weaker on Real monthly cost (5.0/10)
- − Weaker on What they can prescribe (5.0/10)
- − Weaker on What they disclose (7.0/10)
RxSpan MD
Pros
- + Eight longevity treatments, each with a figure attached
- + Price is stated to include consult, medication, supplies, shipping and support
- + Says plainly that a prescription is not guaranteed
Cons
- − Weaker on What they disclose (5.0/10)
- − Weaker on Real monthly cost (5.5/10)
- − Weaker on Prescriber & follow-up (5.5/10)
The bottom line
After scoring all 11 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Hone Health (6.4/10) comes out ahead of RxSpan MD (6.0/10) — but the right choice still depends on what matters most to you.
Choose Hone Health if you want best for clinical oversight — from $175/mo.
Visit Hone Health →Choose RxSpan MD if you want this option — from $149/mo.
Visit RxSpan MD →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →
Ready to start longevity care?
Our verdict for this matchup is Hone Health.
Frequently asked questions
Which is better, Hone Health or RxSpan MD?
How much does Hone Health cost vs RxSpan MD?
What is the difference between Hone Health and RxSpan MD?
Does Hone Health or RxSpan MD take insurance?
Related comparisons
Top picks
Best for published pricing
Best for clinical specificity
Best for explaining the category
We email you when a price we track changes.
No spam, no daily digest — just the clinics you're comparing, when their verified price moves.
How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.