LMy Longevity Picks

MadeMed vs RxSpan MD: Which longevity Clinic Is Better in 2026?

11 clinics scoredPrices checked weekly0 paid rankings

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Short answer

MadeMed wins overall, scoring 8.2/10 vs 6.0/10 — mainly on prescriber & follow-up and what they disclose. If price is your priority, RxSpan MD is cheaper at $149/mo.

Our pick: MadeMed

MadeMed wins overall, scoring 8.2/10 vs 6.0/10. If price is your priority, RxSpan MD is cheaper at $149/mo.

Winner
#2 of 11

MadeMed

8.2

Ties the dose to a lab value, and names the marker it uses.

from $169/mo

Visit MadeMed
#10 of 11

RxSpan MD

6.0

The widest longevity menu here, and not one ongoing price.

from $149/mo

Visit RxSpan MD

MadeMed vs RxSpan MD, side by side

FeatureMadeMedRxSpan MD
Our score8.2/106.0/10
Starting price$169/mo$149/mo
Medication typessermorelin-injection, sermorelin-oral, nad-injection, nad-nasal-spray, peptidesnad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue
Best forBest for clinical specificity
Overall ranking#2#10
Real monthly cost (25%)8.05.5
Prescriber & follow-up (30%)8.55.5
What they can prescribe (20%)8.08.5
What they disclose (25%)8.05.0

Sources: MadeMed pricing verified on mademed.com, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

MadeMed

Pros

  • + Board-certified physician consultation included in the price
  • + Requires a lab test before prescribing, and doses sermorelin against your IGF-1
  • + States the dose on every product — 9mg/3mL daily, NAD+ 1000mg across 8 injections a month

Cons

  • Weaker on Real monthly cost (8.0/10)
  • Weaker on What they can prescribe (8.0/10)
  • Weaker on What they disclose (8.0/10)

RxSpan MD

Pros

  • + Eight longevity treatments, each with a figure attached
  • + Price is stated to include consult, medication, supplies, shipping and support
  • + Says plainly that a prescription is not guaranteed

Cons

  • Weaker on What they disclose (5.0/10)
  • Weaker on Real monthly cost (5.5/10)
  • Weaker on Prescriber & follow-up (5.5/10)

The bottom line

After scoring all 11 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), MadeMed (8.2/10) comes out ahead of RxSpan MD (6.0/10) — but the right choice still depends on what matters most to you.

Choose MadeMed if you want best for clinical specificityfrom $169/mo.

Visit MadeMed

Choose RxSpan MD if you want this optionfrom $149/mo.

Visit RxSpan MD

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →

Ready to start longevity care?

Our verdict for this matchup is MadeMed.

Frequently asked questions

Which is better, MadeMed or RxSpan MD?
MadeMed scores higher overall (8.2/10 vs 6.0/10) and is our recommended pick for most people. If price is the priority, RxSpan MD starts at $149/mo.
How much does MadeMed cost vs RxSpan MD?
MadeMed is from $169/mo and RxSpan MD is from $149/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between MadeMed and RxSpan MD?
MadeMed (8.2/10, #2 of 11) and RxSpan MD (6.0/10, #10 of 11) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does MadeMed or RxSpan MD take insurance?
Neither MadeMed nor RxSpan MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs MadeMedHealthRX vs RxSpan MDMadeMed vs Pallas HealthMadeMed vs bmiMDMadeMed vs AgelessMadeMed vs Live Vital
Ranked by score

Top picks

HealthRXfrom $161/mo

Best for published pricing

Ranks 1 of 11 · no commercial relationship
Read the HealthRX review
MadeMedfrom $169/mo

Best for clinical specificity

Ranks 2 of 11 · no commercial relationship
Read the MadeMed review
Pallas Healthfrom $189/mo

Best for explaining the category

Ranks 3 of 11 · no commercial relationship
Read the Pallas Health review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.