LMy Longevity Picks

MadeMed vs RxSpan MD: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

MadeMed wins overall, scoring 8.2/10 vs 6.1/10. Mainly on prescriber & follow-up and what they disclose. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).

Our pick: MadeMed

MadeMed wins overall, scoring 8.2/10 vs 6.1/10. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).

Winner
#2 of 31

MadeMed

8.2

Ties the dose to a lab value, and names the marker it uses.

from $169/mo on a 6-month plan billed $1,014

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#26 of 31

RxSpan MD

6.1

Eight longevity treatments priced, and not one ongoing price.

from $150/mo on a prepaid 12-month plan ($249 month to month)

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MadeMed vs RxSpan MD, side by side

FeatureMadeMedRxSpan MD
Our score8.2/106.1/10
Starting price$169/mo on a 6-month plan billed $1,014$150/mo on a prepaid 12-month plan ($249 month to month)
Medication typessermorelin-injection, sermorelin-oral, nad-injection, nad-nasal-spray, peptidesnad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue
Best forBest for clinical specificity—
Overall ranking#2#26
Real monthly cost (25%)8.06.0
Prescriber & follow-up (30%)8.55.5
What they can prescribe (20%)8.08.5
What they disclose (25%)8.05.0

Sources: MadeMed pricing verified on mademed.com, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

MadeMed

Pros

  • + Board-certified physician consultation included in the price
  • + Requires a lab test before prescribing, and doses sermorelin against your IGF-1
  • + States the dose on every product. 9mg/3mL daily, NAD+ 1000mg across 8 injections a month

Cons

  • − Weaker on Real monthly cost (8.0/10)
  • − Weaker on What they can prescribe (8.0/10)
  • − Weaker on What they disclose (8.0/10)

RxSpan MD

Pros

  • + Eight longevity treatments, each with a figure attached
  • + Price is stated to include consult, medication, supplies, shipping and support
  • + Says plainly that a prescription is not guaranteed

Cons

  • − Weaker on What they disclose (5.0/10)
  • − Weaker on Prescriber & follow-up (5.5/10)
  • − Weaker on Real monthly cost (6.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), MadeMed (8.2/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.

Choose MadeMed if you want best for clinical specificity. From $169/mo on a 6-month plan billed $1,014.

Read Review →

Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).

Visit →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is MadeMed.

RxSpan MD · from $150/mo on a prepaid 12-month plan ($249 month to month)Visit →
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Frequently asked questions

Which is better, MadeMed or RxSpan MD?
MadeMed scores higher overall (8.2/10 vs 6.1/10) and is our recommended pick for most people. If price is the priority, RxSpan MD starts at $150/mo on a prepaid 12-month plan ($249 month to month).
How much does MadeMed cost vs RxSpan MD?
MadeMed is from $169/mo on a 6-month plan billed $1,014 and RxSpan MD is from $150/mo on a prepaid 12-month plan ($249 month to month). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between MadeMed and RxSpan MD?
MadeMed (8.2/10, #2 of 31) and RxSpan MD (6.1/10, #26 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does MadeMed or RxSpan MD take insurance?
Neither MadeMed nor RxSpan MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs MadeMed→HealthRX vs RxSpan MD→MadeMed vs Ivy Rx→MadeMed vs Precision Telemed→MadeMed vs MyDrHank→MadeMed vs AgelessRx→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.