LMy Longevity Picks

MadeMed vs Lttl: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

MadeMed wins overall, scoring 8.2/10 vs 7.4/10. Mainly on prescriber & follow-up and what they disclose. If price is your priority, Lttl is cheaper at $99/mo on a 12-month supply, $1,188 billed up front.

Our pick: MadeMed

MadeMed wins overall, scoring 8.2/10 vs 7.4/10. If price is your priority, Lttl is cheaper at $99/mo on a 12-month supply, $1,188 billed up front.

Winner
#2 of 31

MadeMed

8.2

Ties the dose to a lab value, and names the marker it uses.

from $169/mo on a 6-month plan billed $1,014

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#8 of 31

LLttl

7.4

Prices every plan with the amount billed up front and names its four pharmacies, but the review rating on its pages does not match its Trustpilot record and its refund pages contradict each other.

from $99/mo on a 12-month supply, $1,188 billed up front

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MadeMed vs Lttl, side by side

FeatureMadeMedLttl
Our score8.2/107.4/10
Starting price$169/mo on a 6-month plan billed $1,014$99/mo on a 12-month supply, $1,188 billed up front
Medication typessermorelin-injection, sermorelin-oral, nad-injection, nad-nasal-spray, peptidesnad-injection, nad-nasal-spray, nad-liposomal, sermorelin-injection, glutathione-injection, methylene-blue, mic-b12
Best forBest for clinical specificity—
Overall ranking#2#8
Real monthly cost (25%)8.08.0
Prescriber & follow-up (30%)8.56.5
What they can prescribe (20%)8.08.5
What they disclose (25%)8.07.0

Sources: MadeMed pricing verified on mademed.com, Lttl pricing verified on lttl.com

Pros & cons

MadeMed

Pros

  • + Board-certified physician consultation included in the price
  • + Requires a lab test before prescribing, and doses sermorelin against your IGF-1
  • + States the dose on every product. 9mg/3mL daily, NAD+ 1000mg across 8 injections a month

Cons

  • − Weaker on Real monthly cost (8.0/10)
  • − Weaker on What they can prescribe (8.0/10)
  • − Weaker on What they disclose (8.0/10)

Lttl

Pros

  • + Every plan priced with the amount charged: NAD+ $149 a month month to month, $417 a quarter, $774 for 6 months or $1,188 for 12 months
  • + Names its four partner pharmacies with addresses in its Terms, each with no FDA warning letter on file
  • + Three NAD+ forms (injection, nasal spray, liposomal oral liquid) plus sermorelin, glutathione and methylene blue, at one price for every dose

Cons

  • − Not available in 1 state
  • − Weaker on Prescriber & follow-up (6.5/10)
  • − Weaker on What they disclose (7.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), MadeMed (8.2/10) comes out ahead of Lttl (7.4/10). But the right choice still depends on what matters most to you.

Choose MadeMed if you want best for clinical specificity. From $169/mo on a 6-month plan billed $1,014.

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Choose Lttl if you want this option. From $99/mo on a 12-month supply, $1,188 billed up front.

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Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is MadeMed.

Lttl · from $99/mo on a 12-month supply, $1,188 billed up frontVisit →
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Frequently asked questions

Which is better, MadeMed or Lttl?
MadeMed scores higher overall (8.2/10 vs 7.4/10) and is our recommended pick for most people. If price is the priority, Lttl starts at $99/mo on a 12-month supply, $1,188 billed up front.
How much does MadeMed cost vs Lttl?
MadeMed is from $169/mo on a 6-month plan billed $1,014 and Lttl is from $99/mo on a 12-month supply, $1,188 billed up front. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between MadeMed and Lttl?
MadeMed (8.2/10, #2 of 31) and Lttl (7.4/10, #8 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does MadeMed or Lttl take insurance?
Neither MadeMed nor Lttl typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs MadeMed→HealthRX vs Lttl→MadeMed vs Ivy Rx→MadeMed vs Precision Telemed→MadeMed vs MyDrHank→MadeMed vs AgelessRx→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.