LMy Longevity Picks

MadeMed vs System Labs: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

Summarize this page with

Short answer

MadeMed wins overall, scoring 8.2/10 vs 7.3/10. Mainly on real monthly cost and prescriber & follow-up. If price is your priority, System Labs is cheaper at $149/mo after an $89 first month, billed monthly.

Our pick: MadeMed

MadeMed wins overall, scoring 8.2/10 vs 7.3/10. If price is your priority, System Labs is cheaper at $149/mo after an $89 first month, billed monthly.

Winner
#2 of 31

MadeMed

8.2

Ties the dose to a lab value, and names the marker it uses.

from $169/mo on a 6-month plan billed $1,014

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#9 of 31

System LabsSystem Labs

7.3

Six longevity treatments, and a pricing page that gives two different answers.

from $149/mo after an $89 first month, billed monthly

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MadeMed vs System Labs, side by side

FeatureMadeMedSystem Labs
Our score8.2/107.3/10
Starting price$169/mo on a 6-month plan billed $1,014$149/mo after an $89 first month, billed monthly
Medication typessermorelin-injection, sermorelin-oral, nad-injection, nad-nasal-spray, peptidesnad-injection, nad-nasal, sermorelin-injection, sermorelin-odt, glutathione-injection, glutathione-nasal
Best forBest for clinical specificity—
Overall ranking#2#9
Real monthly cost (25%)8.06.5
Prescriber & follow-up (30%)8.57.0
What they can prescribe (20%)8.08.0
What they disclose (25%)8.08.0

Sources: MadeMed pricing verified on mademed.com, System Labs pricing verified on systemlabs.com

Pros & cons

MadeMed

Pros

  • + Board-certified physician consultation included in the price
  • + Requires a lab test before prescribing, and doses sermorelin against your IGF-1
  • + States the dose on every product. 9mg/3mL daily, NAD+ 1000mg across 8 injections a month

Cons

  • − Weaker on Real monthly cost (8.0/10)
  • − Weaker on What they can prescribe (8.0/10)
  • − Weaker on What they disclose (8.0/10)

System Labs

Pros

    Cons

    • − Weaker on Real monthly cost (6.5/10)
    • − Weaker on Prescriber & follow-up (7.0/10)
    • − Weaker on What they can prescribe (8.0/10)

    The bottom line

    After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), MadeMed (8.2/10) comes out ahead of System Labs (7.3/10). But the right choice still depends on what matters most to you.

    Choose MadeMed if you want best for clinical specificity. From $169/mo on a 6-month plan billed $1,014.

    Read Review →

    Choose System Labs if you want this option. From $149/mo after an $89 first month, billed monthly.

    Visit →

    Editor's overall pick

    Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

    Ready to start longevity care?

    Our verdict for this matchup is MadeMed.

    System Labs · from $149/mo after an $89 first month, billed monthlyVisit →
    See full rankings

    Frequently asked questions

    Which is better, MadeMed or System Labs?
    MadeMed scores higher overall (8.2/10 vs 7.3/10) and is our recommended pick for most people. If price is the priority, System Labs starts at $149/mo after an $89 first month, billed monthly.
    How much does MadeMed cost vs System Labs?
    MadeMed is from $169/mo on a 6-month plan billed $1,014 and System Labs is from $149/mo after an $89 first month, billed monthly. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
    What is the difference between MadeMed and System Labs?
    MadeMed (8.2/10, #2 of 31) and System Labs (7.3/10, #9 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
    Does MadeMed or System Labs take insurance?
    Neither MadeMed nor System Labs typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

    Related comparisons

    HealthRX vs MadeMed→HealthRX vs System Labs→MadeMed vs Ivy Rx→MadeMed vs Precision Telemed→MadeMed vs MyDrHank→MadeMed vs AgelessRx→
    Ranked by score

    Top picks

    HealthRXfrom $161/mo on a 1-month plan, renewing monthly

    Published prices on every product

    Paid link · ranks 1 of 31 on our methodology either way
    Visit →Read review
    MadeMedfrom $169/mo on a 6-month plan billed $1,014

    Best for clinical specificity

    Ranks 2 of 31 · no commercial relationship
    Read the MadeMed review
    Ivy RxIvy Rxfrom $175 with no billing period stated

    Best named clinical oversight

    Ranks 3 of 31 · no commercial relationship
    Read the Ivy Rx review

    One of these earns us a commission if you sign up. Scores are unaffected; partners are listed first at equal displayed scores. How this works →

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    How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.