LMy Longevity Picks

MadeMed vs System Labs: Which longevity Clinic Is Better in 2026?

21 clinics scoredPrices checked weekly0 paid rankings

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Short answer

MadeMed wins overall, scoring 8.2/10 vs 7.2/10 — mainly on real monthly cost and prescriber & follow-up. If price is your priority, System Labs is cheaper at $149/mo.

Our pick: MadeMed

MadeMed wins overall, scoring 8.2/10 vs 7.2/10. If price is your priority, System Labs is cheaper at $149/mo.

Winner
#2 of 21

MadeMed

8.2

Ties the dose to a lab value, and names the marker it uses.

from $169/mo

Visit MadeMed
#6 of 21

System Labs

7.2

Six longevity treatments, and a pricing page that gives two different answers.

from $149/mo

Visit System Labs

MadeMed vs System Labs, side by side

FeatureMadeMedSystem Labs
Our score8.2/107.2/10
Starting price$169/mo$149/mo
Medication typessermorelin-injection, sermorelin-oral, nad-injection, nad-nasal-spray, peptidesnad-injection, nad-nasal, sermorelin-injection, sermorelin-odt, glutathione-injection, glutathione-nasal
Best forBest for clinical specificity
Overall ranking#2#6
Real monthly cost (25%)8.06.0
Prescriber & follow-up (30%)8.57.0
What they can prescribe (20%)8.08.0
What they disclose (25%)8.08.0

Sources: MadeMed pricing verified on mademed.com, System Labs pricing verified on systemlabs.com

Pros & cons

MadeMed

Pros

  • + Board-certified physician consultation included in the price
  • + Requires a lab test before prescribing, and doses sermorelin against your IGF-1
  • + States the dose on every product — 9mg/3mL daily, NAD+ 1000mg across 8 injections a month

Cons

  • Weaker on Real monthly cost (8.0/10)
  • Weaker on What they can prescribe (8.0/10)
  • Weaker on What they disclose (8.0/10)

System Labs

Pros

    Cons

    • Weaker on Real monthly cost (6.0/10)
    • Weaker on Prescriber & follow-up (7.0/10)
    • Weaker on What they can prescribe (8.0/10)

    The bottom line

    After scoring all 21 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), MadeMed (8.2/10) comes out ahead of System Labs (7.2/10) — but the right choice still depends on what matters most to you.

    Choose MadeMed if you want best for clinical specificityfrom $169/mo.

    Visit MadeMed

    Choose System Labs if you want this optionfrom $149/mo.

    Visit System Labs

    Editor's overall pick

    Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →

    Ready to start longevity care?

    Our verdict for this matchup is MadeMed.

    Frequently asked questions

    Which is better, MadeMed or System Labs?
    MadeMed scores higher overall (8.2/10 vs 7.2/10) and is our recommended pick for most people. If price is the priority, System Labs starts at $149/mo.
    How much does MadeMed cost vs System Labs?
    MadeMed is from $169/mo and System Labs is from $149/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
    What is the difference between MadeMed and System Labs?
    MadeMed (8.2/10, #2 of 21) and System Labs (7.2/10, #6 of 21) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
    Does MadeMed or System Labs take insurance?
    Neither MadeMed nor System Labs typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

    Related comparisons

    HealthRX vs MadeMedHealthRX vs System LabsMadeMed vs Pallas HealthMadeMed vs MyDrHankMadeMed vs EmbodyMadeMed vs Luvo Health
    Ranked by score

    Top picks

    HealthRXfrom $161/mo

    Best for published pricing

    Paid link · ranks 1 of 21 on our methodology either way
    Go to HealthRXRead review
    MadeMedfrom $169/mo

    Best for clinical specificity

    Ranks 2 of 21 · no commercial relationship
    Read the MadeMed review
    Pallas Healthfrom $189/mo

    Best for explaining the category

    Paid link · ranks 3 of 21 on our methodology either way
    Go to Pallas HealthRead review

    2 of these earn us a commission if you sign up. Scores and rank are unaffected. How this works →

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    No spam, no daily digest — just the clinics you're comparing, when their verified price moves.

    How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.

    Top Pick · $161/mo

    HealthRX

    Get →

    $161/mo is a real, ongoing rate on the plan it applies to — our evidence shows no sign it's a promotional rate that rises later.