LMy Longevity Picks

System Labs vs YourEra: Which longevity Clinic Is Better in 2026?

21 clinics scoredPrices checked weekly0 paid rankings

Summarize this page with

Short answer

System Labs wins overall, scoring 7.2/10 vs 6.7/10 — mainly on what they can prescribe and real monthly cost.

Our pick: System Labs

System Labs wins overall, scoring 7.2/10 vs 6.7/10.

Winner
#6 of 21

System Labs

7.2

Six longevity treatments, and a pricing page that gives two different answers.

from $149/mo

Visit System Labs
#13 of 21

YourEra

6.7

The only clinic here with a LegitScript certification, and the only one whose affiliate link never mentions the product we ranked it for.

from $170/mo

Visit YourEra

System Labs vs YourEra, side by side

FeatureSystem LabsYourEra
Our score7.2/106.7/10
Starting price$149/mo$170/mo
Medication typesnad-injection, nad-nasal, sermorelin-injection, sermorelin-odt, glutathione-injection, glutathione-nasalnad-injection
Best for
Overall ranking#6#13
Real monthly cost (25%)6.07.0
Prescriber & follow-up (30%)7.07.0
What they can prescribe (20%)8.05.5
What they disclose (25%)8.07.0

Sources: System Labs pricing verified on systemlabs.com, YourEra pricing verified on yourera.com

Pros & cons

System Labs

Pros

    Cons

    • Weaker on Real monthly cost (6.0/10)
    • Weaker on Prescriber & follow-up (7.0/10)
    • Weaker on What they can prescribe (8.0/10)

    YourEra

    Pros

    • + Flat pricing stated outright — same price at every dose, visit and shipping included
    • + LegitScript-certified, an external check no other clinic in this set carries
    • + Compounded-drug FDA disclosure published in its own words, not buried

    Cons

    • Weaker on What they can prescribe (5.5/10)
    • Weaker on Real monthly cost (7.0/10)
    • Weaker on Prescriber & follow-up (7.0/10)

    The bottom line

    After scoring all 21 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), System Labs (7.2/10) comes out ahead of YourEra (6.7/10) — but the right choice still depends on what matters most to you.

    Choose System Labs if you want this optionfrom $149/mo.

    Visit System Labs

    Choose YourEra if you want this optionfrom $170/mo.

    Visit YourEra

    Editor's overall pick

    Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →

    Ready to start longevity care?

    Our verdict for this matchup is System Labs.

    Frequently asked questions

    Which is better, System Labs or YourEra?
    System Labs scores higher overall (7.2/10 vs 6.7/10) and is our recommended pick for most people. System Labs also has the lower starting price at $149/mo.
    How much does System Labs cost vs YourEra?
    System Labs is from $149/mo and YourEra is from $170/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
    What is the difference between System Labs and YourEra?
    System Labs (7.2/10, #6 of 21) and YourEra (6.7/10, #13 of 21) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
    Does System Labs or YourEra take insurance?
    Neither System Labs nor YourEra typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

    Related comparisons

    HealthRX vs System LabsHealthRX vs YourEraMadeMed vs System LabsMadeMed vs YourEraPallas Health vs System LabsPallas Health vs YourEra
    Ranked by score

    Top picks

    HealthRXfrom $161/mo

    Best for published pricing

    Paid link · ranks 1 of 21 on our methodology either way
    Go to HealthRXRead review
    MadeMedfrom $169/mo

    Best for clinical specificity

    Ranks 2 of 21 · no commercial relationship
    Read the MadeMed review
    Pallas Healthfrom $189/mo

    Best for explaining the category

    Paid link · ranks 3 of 21 on our methodology either way
    Go to Pallas HealthRead review

    2 of these earn us a commission if you sign up. Scores and rank are unaffected. How this works →

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    No spam, no daily digest — just the clinics you're comparing, when their verified price moves.

    How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.

    Top Pick · $161/mo

    HealthRX

    Get →

    $161/mo is a real, ongoing rate on the plan it applies to — our evidence shows no sign it's a promotional rate that rises later.