AgelessRx vs He & She MD: Which longevity Clinic Is Better in 2026?
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Short answer
AgelessRx wins overall, scoring 7.7/10 vs 6.8/10. Mainly on prescriber & follow-up and what they disclose.
A Michigan longevity telehealth service with a named medical director and the rare combination of NAD+, rapamycin with lab work included, metformin and low dose naltrexone on one menu.
from $149/mo on a 3-month plan billed in full, after a $79 first month
Read Review
He & She MD
Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.
from $229/mo on a monthly plan ($139/mo on the annual plan)
Read ReviewAgelessRx vs He & She MD, side by side
| Feature | AgelessRx | He & She MD |
|---|---|---|
| Our score | 7.7/10 | 6.8/10 |
| Starting price | $149/mo on a 3-month plan billed in full, after a $79 first month | $229/mo on a monthly plan ($139/mo on the annual plan) |
| Medication types | metformin, nad-injection, nad-nasal-spray, rapamycin | nad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream |
| Best for | — | — |
| Overall ranking | #6 | #19 |
| Real monthly cost (25%) | 7.5 | 7.0 |
| Prescriber & follow-up (30%) | 7.5 | 6.0 |
| What they can prescribe (20%) | 8.5 | 8.5 |
| What they disclose (25%) | 7.5 | 6.0 |
Sources: AgelessRx pricing verified on agelessrx.com, He & She MD pricing verified on heandshemd.com
Pros & cons
AgelessRx
Pros
- + Rapamycin at $65/month with "Baseline and ongoing blood work included"
- + NAD+ injection from $79/mo on a 3-month plan; nasal spray also offered
- + Names its CEO, Anar Isman, and its Medical Director, Dr. Jenell Decker, MD, with a published Ann Arbor address
Cons
- − Weaker on Real monthly cost (7.5/10)
- − Weaker on Prescriber & follow-up (7.5/10)
- − Weaker on What they disclose (7.5/10)
He & She MD
Pros
- + Full commitment ladder published before intake, all four tiers
- + NAD+ dose published (1000 mg)
- + Six longevity products across injection, cream and nasal spray
Cons
- − Weaker on Prescriber & follow-up (6.0/10)
- − Weaker on What they disclose (6.0/10)
- − Weaker on Real monthly cost (7.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), AgelessRx (7.7/10) comes out ahead of He & She MD (6.8/10). But the right choice still depends on what matters most to you.
Choose AgelessRx if you want this option. From $149/mo on a 3-month plan billed in full, after a $79 first month.
Read Review →Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).
Read Review →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is AgelessRx.
Frequently asked questions
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.