LMy Longevity Picks

AgelessRx vs System Labs: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

Summarize this page with

Short answer

AgelessRx wins overall, scoring 7.7/10 vs 7.3/10. Mainly on real monthly cost and prescriber & follow-up.

Our pick: AgelessRx

AgelessRx wins overall, scoring 7.7/10 vs 7.3/10.

Winner
#6 of 31

AgelessRx

7.7

A Michigan longevity telehealth service with a named medical director and the rare combination of NAD+, rapamycin with lab work included, metformin and low dose naltrexone on one menu.

from $149/mo on a 3-month plan billed in full, after a $79 first month

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#9 of 31

System LabsSystem Labs

7.3

Six longevity treatments, and a pricing page that gives two different answers.

from $149/mo after an $89 first month, billed monthly

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AgelessRx vs System Labs, side by side

FeatureAgelessRxSystem Labs
Our score7.7/107.3/10
Starting price$149/mo on a 3-month plan billed in full, after a $79 first month$149/mo after an $89 first month, billed monthly
Medication typesmetformin, nad-injection, nad-nasal-spray, rapamycinnad-injection, nad-nasal, sermorelin-injection, sermorelin-odt, glutathione-injection, glutathione-nasal
Best for——
Overall ranking#6#9
Real monthly cost (25%)7.56.5
Prescriber & follow-up (30%)7.57.0
What they can prescribe (20%)8.58.0
What they disclose (25%)7.58.0

Sources: AgelessRx pricing verified on agelessrx.com, System Labs pricing verified on systemlabs.com

Pros & cons

AgelessRx

Pros

  • + Rapamycin at $65/month with "Baseline and ongoing blood work included"
  • + NAD+ injection from $79/mo on a 3-month plan; nasal spray also offered
  • + Names its CEO, Anar Isman, and its Medical Director, Dr. Jenell Decker, MD, with a published Ann Arbor address

Cons

  • − Weaker on Real monthly cost (7.5/10)
  • − Weaker on Prescriber & follow-up (7.5/10)
  • − Weaker on What they disclose (7.5/10)

System Labs

Pros

    Cons

    • − Weaker on Real monthly cost (6.5/10)
    • − Weaker on Prescriber & follow-up (7.0/10)
    • − Weaker on What they can prescribe (8.0/10)

    The bottom line

    After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), AgelessRx (7.7/10) comes out ahead of System Labs (7.3/10). But the right choice still depends on what matters most to you.

    Choose AgelessRx if you want this option. From $149/mo on a 3-month plan billed in full, after a $79 first month.

    Read Review →

    Choose System Labs if you want this option. From $149/mo after an $89 first month, billed monthly.

    Visit →

    Editor's overall pick

    Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

    Ready to start longevity care?

    Our verdict for this matchup is AgelessRx.

    AgelessRxRead Review
    System Labs · from $149/mo after an $89 first month, billed monthlyVisit →
    See full rankings

    Frequently asked questions

    Which is better, AgelessRx or System Labs?
    AgelessRx scores higher overall (7.7/10 vs 7.3/10) and is our recommended pick for most people. AgelessRx also has the lower starting price at $149/mo on a 3-month plan billed in full, after a $79 first month.
    How much does AgelessRx cost vs System Labs?
    AgelessRx is from $149/mo on a 3-month plan billed in full, after a $79 first month and System Labs is from $149/mo after an $89 first month, billed monthly. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
    What is the difference between AgelessRx and System Labs?
    AgelessRx (7.7/10, #6 of 31) and System Labs (7.3/10, #9 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
    Does AgelessRx or System Labs take insurance?
    Neither AgelessRx nor System Labs typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

    Related comparisons

    HealthRX vs AgelessRx→HealthRX vs System Labs→MadeMed vs AgelessRx→MadeMed vs System Labs→Ivy Rx vs AgelessRx→Ivy Rx vs System Labs→
    Ranked by score

    Top picks

    HealthRXfrom $161/mo on a 1-month plan, renewing monthly

    Published prices on every product

    Paid link · ranks 1 of 31 on our methodology either way
    Visit →Read review
    MadeMedfrom $169/mo on a 6-month plan billed $1,014

    Best for clinical specificity

    Ranks 2 of 31 · no commercial relationship
    Read the MadeMed review
    Ivy RxIvy Rxfrom $175 with no billing period stated

    Best named clinical oversight

    Ranks 3 of 31 · no commercial relationship
    Read the Ivy Rx review

    One of these earns us a commission if you sign up. Scores are unaffected; partners are listed first at equal displayed scores. How this works →

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    How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.