LMy Longevity Picks

Enhanced vs He & She MD: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

Summarize this page with

Short answer

Enhanced wins overall, scoring 7.1/10 vs 6.8/10. Mainly on prescriber & follow-up and what they can prescribe.

Our pick: Enhanced

Enhanced wins overall, scoring 7.1/10 vs 6.8/10.

Enhanced · from $143/mo on a 6-month supply

Winner
#13 of 31

EnhancedEnhanced

7.1

Prices NAD+, sermorelin and GHK-Cu by supply length on its own pages, but sends you to a third-party telehealth platform for its prescribers, pharmacies and states.

from $143/mo on a 6-month supply

Visit →
#19 of 31

He & She MDHe & She MD

6.8

Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.

from $229/mo on a monthly plan ($139/mo on the annual plan)

Read Review

Enhanced vs He & She MD, side by side

FeatureEnhancedHe & She MD
Our score7.1/106.8/10
Starting price$143/mo on a 6-month supply$229/mo on a monthly plan ($139/mo on the annual plan)
Medication typesnad-injection, sermorelin-injection, ghk-cunad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream
Best for——
Overall ranking#13#19
Real monthly cost (25%)7.57.0
Prescriber & follow-up (30%)7.06.0
What they can prescribe (20%)7.58.5
What they disclose (25%)6.56.0

Sources: Enhanced pricing verified on enhanced.com, He & She MD pricing verified on heandshemd.com

Pros & cons

Enhanced

Pros

  • + Every price is published by supply length: NAD+ $169, $159 or $143 a month for 1, 3 or 6 months
  • + States the dose (NAD+ 300 to 500 mg a week, sermorelin 250 to 400 mcg nightly) and what the price includes: medication, clinician and ongoing care
  • + Names its legal entity with an address (Enhanced US LLC, New York) and the telehealth groups that provide care

Cons

  • − Weaker on What they disclose (6.5/10)
  • − Weaker on Prescriber & follow-up (7.0/10)
  • − Weaker on Real monthly cost (7.5/10)

He & She MD

Pros

  • + Full commitment ladder published before intake, all four tiers
  • + NAD+ dose published (1000 mg)
  • + Six longevity products across injection, cream and nasal spray

Cons

  • − Weaker on Prescriber & follow-up (6.0/10)
  • − Weaker on What they disclose (6.0/10)
  • − Weaker on Real monthly cost (7.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Enhanced (7.1/10) comes out ahead of He & She MD (6.8/10). But the right choice still depends on what matters most to you.

Choose Enhanced if you want this option. From $143/mo on a 6-month supply.

Visit →

Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).

Read Review →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is Enhanced.

Enhanced · from $143/mo on a 6-month supplyVisit →
He & She MDRead Review
See full rankings

Frequently asked questions

Which is better, Enhanced or He & She MD?
Enhanced scores higher overall (7.1/10 vs 6.8/10) and is our recommended pick for most people. Enhanced also has the lower starting price at $143/mo on a 6-month supply.
How much does Enhanced cost vs He & She MD?
Enhanced is from $143/mo on a 6-month supply and He & She MD is from $229/mo on a monthly plan ($139/mo on the annual plan). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Enhanced and He & She MD?
Enhanced (7.1/10, #13 of 31) and He & She MD (6.8/10, #19 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Enhanced or He & She MD take insurance?
Neither Enhanced nor He & She MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs Enhanced→HealthRX vs He & She MD→MadeMed vs Enhanced→MadeMed vs He & She MD→Ivy Rx vs Enhanced→Ivy Rx vs He & She MD→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

One of these earns us a commission if you sign up. Scores are unaffected; partners are listed first at equal displayed scores. How this works →

We email you when a price we track changes.

No spam, no daily digest. Just the clinics you're comparing, when their verified price moves.

How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.