He & She MD vs RxSpan MD: Which longevity Clinic Is Better in 2026?
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Short answer
He & She MD wins overall, scoring 6.8/10 vs 6.1/10. Mainly on real monthly cost and what they disclose. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).
He & She MD wins overall, scoring 6.8/10 vs 6.1/10. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).
He & She MD
Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.
from $229/mo on a monthly plan ($139/mo on the annual plan)
Read Review
Eight longevity treatments priced, and not one ongoing price.
from $150/mo on a prepaid 12-month plan ($249 month to month)
Visit →He & She MD vs RxSpan MD, side by side
| Feature | He & She MD | RxSpan MD |
|---|---|---|
| Our score | 6.8/10 | 6.1/10 |
| Starting price | $229/mo on a monthly plan ($139/mo on the annual plan) | $150/mo on a prepaid 12-month plan ($249 month to month) |
| Medication types | nad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream | nad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue |
| Best for | — | — |
| Overall ranking | #19 | #26 |
| Real monthly cost (25%) | 7.0 | 6.0 |
| Prescriber & follow-up (30%) | 6.0 | 5.5 |
| What they can prescribe (20%) | 8.5 | 8.5 |
| What they disclose (25%) | 6.0 | 5.0 |
Sources: He & She MD pricing verified on heandshemd.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
He & She MD
Pros
- + Full commitment ladder published before intake, all four tiers
- + NAD+ dose published (1000 mg)
- + Six longevity products across injection, cream and nasal spray
Cons
- − Weaker on Prescriber & follow-up (6.0/10)
- − Weaker on What they disclose (6.0/10)
- − Weaker on Real monthly cost (7.0/10)
RxSpan MD
Pros
- + Eight longevity treatments, each with a figure attached
- + Price is stated to include consult, medication, supplies, shipping and support
- + Says plainly that a prescription is not guaranteed
Cons
- − Weaker on What they disclose (5.0/10)
- − Weaker on Prescriber & follow-up (5.5/10)
- − Weaker on Real monthly cost (6.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), He & She MD (6.8/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.
Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).
Read Review →Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).
Visit →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is He & She MD.
Frequently asked questions
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.