He & She MD vs RxSpan MD: Which longevity Clinic Is Better in 2026?
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Short answer
He & She MD wins overall, scoring 6.8/10 vs 6.0/10 — mainly on real monthly cost and what they disclose. If price is your priority, RxSpan MD is cheaper at $149/mo.
He & She MD wins overall, scoring 6.8/10 vs 6.0/10. If price is your priority, RxSpan MD is cheaper at $149/mo.
He & She MD
Publishes the whole ladder and the dose — then quotes a different annual price on its own two longevity pages.
from $229/mo
Visit He & She MDRxSpan MD
The widest longevity menu here, and not one ongoing price.
from $149/mo
Visit RxSpan MDHe & She MD vs RxSpan MD, side by side
| Feature | He & She MD | RxSpan MD |
|---|---|---|
| Our score | 6.8/10 | 6.0/10 |
| Starting price | $229/mo | $149/mo |
| Medication types | nad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream | nad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue |
| Best for | — | — |
| Overall ranking | #12 | #17 |
| Real monthly cost (25%) | 7.0 | 5.5 |
| Prescriber & follow-up (30%) | 6.0 | 5.5 |
| What they can prescribe (20%) | 8.5 | 8.5 |
| What they disclose (25%) | 6.0 | 5.0 |
Sources: He & She MD pricing verified on heandshemd.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
He & She MD
Pros
- + Full commitment ladder published before intake, all four tiers
- + NAD+ dose published (1000 mg), which most of this set does not
- + Six longevity products across injection, cream and nasal spray
Cons
- − Weaker on Prescriber & follow-up (6.0/10)
- − Weaker on What they disclose (6.0/10)
- − Weaker on Real monthly cost (7.0/10)
RxSpan MD
Pros
- + Eight longevity treatments, each with a figure attached
- + Price is stated to include consult, medication, supplies, shipping and support
- + Says plainly that a prescription is not guaranteed
Cons
- − Weaker on What they disclose (5.0/10)
- − Weaker on Real monthly cost (5.5/10)
- − Weaker on Prescriber & follow-up (5.5/10)
The bottom line
After scoring all 21 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), He & She MD (6.8/10) comes out ahead of RxSpan MD (6.0/10) — but the right choice still depends on what matters most to you.
Choose He & She MD if you want this option — from $229/mo.
Visit He & She MD →Choose RxSpan MD if you want this option — from $149/mo.
Visit RxSpan MD →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →
Ready to start longevity care?
Our verdict for this matchup is He & She MD.
Frequently asked questions
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