LMy Longevity Picks

Live Vital vs He & She MD: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

Live Vital and He & She MD tie at 6.8/10, so it comes down to price and what they can prescribe and prescriber & follow-up. Live Vital is cheaper at $149/mo on a 3-month protocol ($447 total).

Nearly tied: Live Vital vs He & She MD

Live Vital and He & She MD are essentially tied, 6.8/10 vs 6.8/10.

Live Vital · from $149/mo on a 3-month protocol ($447 total)

Winner
#17 of 31

Live Vital

6.8

Names the physician who reviews your intake, and shows the protocol total next to the monthly price.

from $149/mo on a 3-month protocol ($447 total)

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#19 of 31

He & She MDHe & She MD

6.8

Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.

from $229/mo on a monthly plan ($139/mo on the annual plan)

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Live Vital vs He & She MD, side by side

FeatureLive VitalHe & She MD
Our score6.8/106.8/10
Starting price$149/mo on a 3-month protocol ($447 total)$229/mo on a monthly plan ($139/mo on the annual plan)
Medication typesnad-injection, glutathione-injection, peptidesnad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream
Best forBest for a named prescriber—
Overall ranking#17#19
Real monthly cost (25%)7.57.0
Prescriber & follow-up (30%)7.06.0
What they can prescribe (20%)6.58.5
What they disclose (25%)6.06.0

Sources: Live Vital pricing verified on livevital.io, He & She MD pricing verified on heandshemd.com

Pros & cons

Live Vital

Pros

  • + NAD+ at $149/mo and glutathione at $99/mo, each with the three-month total shown
  • + Names its reviewing physician publicly rather than referring to a network
  • + Prepared by a licensed US pharmacy, with unlimited messaging to the care team

Cons

  • − Weaker on What they disclose (6.0/10)
  • − Weaker on What they can prescribe (6.5/10)
  • − Weaker on Prescriber & follow-up (7.0/10)

He & She MD

Pros

  • + Full commitment ladder published before intake, all four tiers
  • + NAD+ dose published (1000 mg)
  • + Six longevity products across injection, cream and nasal spray

Cons

  • − Weaker on Prescriber & follow-up (6.0/10)
  • − Weaker on What they disclose (6.0/10)
  • − Weaker on Real monthly cost (7.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Live Vital and He & She MD are essentially tied (6.8 vs 6.8/10). There is no clear overall winner here, so the right choice comes down to what matters most to you.

Choose Live Vital if you want best for a named prescriber. From $149/mo on a 3-month protocol ($447 total).

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Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).

Read Review →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Live Vital and He & She MD are essentially tied. Either is a solid choice.

Live Vital · from $149/mo on a 3-month protocol ($447 total)Visit →
He & She MDRead Review
See full rankings

Frequently asked questions

Which is better, Live Vital or He & She MD?
Live Vital and He & She MD are essentially tied (6.8/10 vs 6.8/10). There's no clear overall winner. If price is the deciding factor, Live Vital starts at $149/mo on a 3-month protocol ($447 total).
How much does Live Vital cost vs He & She MD?
Live Vital is from $149/mo on a 3-month protocol ($447 total) and He & She MD is from $229/mo on a monthly plan ($139/mo on the annual plan). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Live Vital and He & She MD?
Live Vital (6.8/10, #17 of 31) and He & She MD (6.8/10, #19 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Live Vital or He & She MD take insurance?
Neither Live Vital nor He & She MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs Live Vital→HealthRX vs He & She MD→MadeMed vs Live Vital→MadeMed vs He & She MD→Ivy Rx vs Live Vital→Ivy Rx vs He & She MD→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.