LMy Longevity Picks

Live Vital vs RxSpan MD: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

Live Vital wins overall, scoring 6.8/10 vs 6.1/10. Mainly on what they can prescribe and real monthly cost.

Our pick: Live Vital

Live Vital wins overall, scoring 6.8/10 vs 6.1/10.

Live Vital · from $149/mo on a 3-month protocol ($447 total)

Winner
#17 of 31

Live Vital

6.8

Names the physician who reviews your intake, and shows the protocol total next to the monthly price.

from $149/mo on a 3-month protocol ($447 total)

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#26 of 31

RxSpan MD

6.1

Eight longevity treatments priced, and not one ongoing price.

from $150/mo on a prepaid 12-month plan ($249 month to month)

Visit →

Live Vital vs RxSpan MD, side by side

FeatureLive VitalRxSpan MD
Our score6.8/106.1/10
Starting price$149/mo on a 3-month protocol ($447 total)$150/mo on a prepaid 12-month plan ($249 month to month)
Medication typesnad-injection, glutathione-injection, peptidesnad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue
Best forBest for a named prescriber—
Overall ranking#17#26
Real monthly cost (25%)7.56.0
Prescriber & follow-up (30%)7.05.5
What they can prescribe (20%)6.58.5
What they disclose (25%)6.05.0

Sources: Live Vital pricing verified on livevital.io, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

Live Vital

Pros

  • + NAD+ at $149/mo and glutathione at $99/mo, each with the three-month total shown
  • + Names its reviewing physician publicly rather than referring to a network
  • + Prepared by a licensed US pharmacy, with unlimited messaging to the care team

Cons

  • − Weaker on What they disclose (6.0/10)
  • − Weaker on What they can prescribe (6.5/10)
  • − Weaker on Prescriber & follow-up (7.0/10)

RxSpan MD

Pros

  • + Eight longevity treatments, each with a figure attached
  • + Price is stated to include consult, medication, supplies, shipping and support
  • + Says plainly that a prescription is not guaranteed

Cons

  • − Weaker on What they disclose (5.0/10)
  • − Weaker on Prescriber & follow-up (5.5/10)
  • − Weaker on Real monthly cost (6.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Live Vital (6.8/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.

Choose Live Vital if you want best for a named prescriber. From $149/mo on a 3-month protocol ($447 total).

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Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).

Visit →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is Live Vital.

Live Vital · from $149/mo on a 3-month protocol ($447 total)Visit →
RxSpan MD · from $150/mo on a prepaid 12-month plan ($249 month to month)Visit →
See full rankings

Frequently asked questions

Which is better, Live Vital or RxSpan MD?
Live Vital scores higher overall (6.8/10 vs 6.1/10) and is our recommended pick for most people. Live Vital also has the lower starting price at $149/mo on a 3-month protocol ($447 total).
How much does Live Vital cost vs RxSpan MD?
Live Vital is from $149/mo on a 3-month protocol ($447 total) and RxSpan MD is from $150/mo on a prepaid 12-month plan ($249 month to month). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Live Vital and RxSpan MD?
Live Vital (6.8/10, #17 of 31) and RxSpan MD (6.1/10, #26 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Live Vital or RxSpan MD take insurance?
Neither Live Vital nor RxSpan MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs Live Vital→HealthRX vs RxSpan MD→MadeMed vs Live Vital→MadeMed vs RxSpan MD→Ivy Rx vs Live Vital→Ivy Rx vs RxSpan MD→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.