LMy Longevity Picks

Live Vital vs RxSpan MD: Which longevity Clinic Is Better in 2026?

11 clinics scoredPrices checked weekly0 paid rankings

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Short answer

Live Vital wins overall, scoring 6.8/10 vs 6.0/10 — mainly on real monthly cost and what they can prescribe.

Our pick: Live Vital

Live Vital wins overall, scoring 6.8/10 vs 6.0/10.

Winner
#6 of 11

Live Vital

6.8

Names the physician who reviews your intake, and shows the protocol total next to the monthly price.

from $149/mo

Visit Live Vital
#10 of 11

RxSpan MD

6.0

The widest longevity menu here, and not one ongoing price.

from $149/mo

Visit RxSpan MD

Live Vital vs RxSpan MD, side by side

FeatureLive VitalRxSpan MD
Our score6.8/106.0/10
Starting price$149/mo$149/mo
Medication typesnad-injection, glutathione-injection, peptidesnad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue
Best forBest for a named prescriber
Overall ranking#6#10
Real monthly cost (25%)7.55.5
Prescriber & follow-up (30%)7.05.5
What they can prescribe (20%)6.58.5
What they disclose (25%)6.05.0

Sources: Live Vital pricing verified on livevital.io, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

Live Vital

Pros

  • + NAD+ at $149/mo and glutathione at $119/mo, each with the three-month total shown
  • + Names its reviewing physician publicly rather than referring to a network
  • + Prepared by a licensed US pharmacy, with unlimited messaging to the care team

Cons

  • Weaker on What they disclose (6.0/10)
  • Weaker on What they can prescribe (6.5/10)
  • Weaker on Prescriber & follow-up (7.0/10)

RxSpan MD

Pros

  • + Eight longevity treatments, each with a figure attached
  • + Price is stated to include consult, medication, supplies, shipping and support
  • + Says plainly that a prescription is not guaranteed

Cons

  • Weaker on What they disclose (5.0/10)
  • Weaker on Real monthly cost (5.5/10)
  • Weaker on Prescriber & follow-up (5.5/10)

The bottom line

After scoring all 11 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Live Vital (6.8/10) comes out ahead of RxSpan MD (6.0/10) — but the right choice still depends on what matters most to you.

Choose Live Vital if you want best for a named prescriberfrom $149/mo.

Visit Live Vital

Choose RxSpan MD if you want this optionfrom $149/mo.

Visit RxSpan MD

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →

Ready to start longevity care?

Our verdict for this matchup is Live Vital.

Frequently asked questions

Which is better, Live Vital or RxSpan MD?
Live Vital scores higher overall (6.8/10 vs 6.0/10) and is our recommended pick for most people. Live Vital also has the lower starting price at $149/mo.
How much does Live Vital cost vs RxSpan MD?
Live Vital is from $149/mo and RxSpan MD is from $149/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Live Vital and RxSpan MD?
Live Vital (6.8/10, #6 of 11) and RxSpan MD (6.0/10, #10 of 11) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Live Vital or RxSpan MD take insurance?
Neither Live Vital nor RxSpan MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs Live VitalHealthRX vs RxSpan MDMadeMed vs Live VitalMadeMed vs RxSpan MDPallas Health vs Live VitalPallas Health vs RxSpan MD
Ranked by score

Top picks

HealthRXfrom $161/mo

Best for published pricing

Ranks 1 of 11 · no commercial relationship
Read the HealthRX review
MadeMedfrom $169/mo

Best for clinical specificity

Ranks 2 of 11 · no commercial relationship
Read the MadeMed review
Pallas Healthfrom $189/mo

Best for explaining the category

Ranks 3 of 11 · no commercial relationship
Read the Pallas Health review

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.