System Labs vs He & She MD: Which longevity Clinic Is Better in 2026?
Summarize this page with
Short answer
System Labs wins overall, scoring 7.2/10 vs 6.8/10 — mainly on what they disclose and real monthly cost.
System Labs wins overall, scoring 7.2/10 vs 6.8/10.
System Labs
Six longevity treatments, and a pricing page that gives two different answers.
from $149/mo
Visit System LabsHe & She MD
Publishes the whole ladder and the dose — then quotes a different annual price on its own two longevity pages.
from $229/mo
Visit He & She MDSystem Labs vs He & She MD, side by side
| Feature | System Labs | He & She MD |
|---|---|---|
| Our score | 7.2/10 | 6.8/10 |
| Starting price | $149/mo | $229/mo |
| Medication types | nad-injection, nad-nasal, sermorelin-injection, sermorelin-odt, glutathione-injection, glutathione-nasal | nad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream |
| Best for | — | — |
| Overall ranking | #6 | #12 |
| Real monthly cost (25%) | 6.0 | 7.0 |
| Prescriber & follow-up (30%) | 7.0 | 6.0 |
| What they can prescribe (20%) | 8.0 | 8.5 |
| What they disclose (25%) | 8.0 | 6.0 |
Sources: System Labs pricing verified on systemlabs.com, He & She MD pricing verified on heandshemd.com
Pros & cons
System Labs
Pros
Cons
- − Weaker on Real monthly cost (6.0/10)
- − Weaker on Prescriber & follow-up (7.0/10)
- − Weaker on What they can prescribe (8.0/10)
He & She MD
Pros
- + Full commitment ladder published before intake, all four tiers
- + NAD+ dose published (1000 mg), which most of this set does not
- + Six longevity products across injection, cream and nasal spray
Cons
- − Weaker on Prescriber & follow-up (6.0/10)
- − Weaker on What they disclose (6.0/10)
- − Weaker on Real monthly cost (7.0/10)
The bottom line
After scoring all 21 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), System Labs (7.2/10) comes out ahead of He & She MD (6.8/10) — but the right choice still depends on what matters most to you.
Choose System Labs if you want this option — from $149/mo.
Visit System Labs →Choose He & She MD if you want this option — from $229/mo.
Visit He & She MD →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →
Ready to start longevity care?
Our verdict for this matchup is System Labs.
Frequently asked questions
Which is better, System Labs or He & She MD?
How much does System Labs cost vs He & She MD?
What is the difference between System Labs and He & She MD?
Does System Labs or He & She MD take insurance?
Related comparisons
Top picks
Best for published pricing
Best for clinical specificity
Best for explaining the category
2 of these earn us a commission if you sign up. Scores and rank are unaffected. How this works →
We email you when a price we track changes.
No spam, no daily digest — just the clinics you're comparing, when their verified price moves.
How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.