Willow vs RxSpan MD: Which longevity Clinic Is Better in 2026?
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Short answer
Willow wins overall, scoring 6.5/10 vs 6.1/10. Mainly on what they can prescribe and prescriber & follow-up. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).
Willow wins overall, scoring 6.5/10 vs 6.1/10. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).
Willow · from $199/mo billed monthly until cancelled
Willow
Names its company, 36 physicians and five pharmacies, but not the dose its $199 NAD+ vial contains or which pharmacy makes it.
from $199/mo billed monthly until cancelled
Visit →
Eight longevity treatments priced, and not one ongoing price.
from $150/mo on a prepaid 12-month plan ($249 month to month)
Visit →Willow vs RxSpan MD, side by side
| Feature | Willow | RxSpan MD |
|---|---|---|
| Our score | 6.5/10 | 6.1/10 |
| Starting price | $199/mo billed monthly until cancelled | $150/mo on a prepaid 12-month plan ($249 month to month) |
| Medication types | nad-injection | nad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue |
| Best for | — | — |
| Overall ranking | #21 | #26 |
| Real monthly cost (25%) | 6.0 | 6.0 |
| Prescriber & follow-up (30%) | 7.5 | 5.5 |
| What they can prescribe (20%) | 5.5 | 8.5 |
| What they disclose (25%) | 6.5 | 5.0 |
Sources: Willow pricing verified on startwillow.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
Willow
Pros
- + Names its legal entity with a street address, 36 US-licensed physicians with individual bio pages, and all five partner pharmacies with full addresses
- + One published monthly price that states what it includes: the vial, syringes, needles, doctor access and free shipping
- + States plainly that compounded NAD+ is not FDA-approved, on the product page and its safety page
Cons
- − Weaker on What they can prescribe (5.5/10)
- − Weaker on Real monthly cost (6.0/10)
- − Weaker on What they disclose (6.5/10)
RxSpan MD
Pros
- + Eight longevity treatments, each with a figure attached
- + Price is stated to include consult, medication, supplies, shipping and support
- + Says plainly that a prescription is not guaranteed
Cons
- − Weaker on What they disclose (5.0/10)
- − Weaker on Prescriber & follow-up (5.5/10)
- − Weaker on Real monthly cost (6.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Willow (6.5/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.
Choose Willow if you want this option. From $199/mo billed monthly until cancelled.
Visit →Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).
Visit →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is Willow.
Frequently asked questions
Which is better, Willow or RxSpan MD?
How much does Willow cost vs RxSpan MD?
What is the difference between Willow and RxSpan MD?
Does Willow or RxSpan MD take insurance?
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.