LMy Longevity Picks

YourEra vs RxSpan MD: Which longevity Clinic Is Better in 2026?

21 clinics scoredPrices checked weekly0 paid rankings

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Short answer

YourEra wins overall, scoring 6.7/10 vs 6.0/10 — mainly on what they can prescribe and what they disclose. If price is your priority, RxSpan MD is cheaper at $149/mo.

Our pick: YourEra

YourEra wins overall, scoring 6.7/10 vs 6.0/10. If price is your priority, RxSpan MD is cheaper at $149/mo.

Winner
#13 of 21

YourEra

6.7

The only clinic here with a LegitScript certification, and the only one whose affiliate link never mentions the product we ranked it for.

from $170/mo

Visit YourEra
#17 of 21

RxSpan MD

6.0

The widest longevity menu here, and not one ongoing price.

from $149/mo

Visit RxSpan MD

YourEra vs RxSpan MD, side by side

FeatureYourEraRxSpan MD
Our score6.7/106.0/10
Starting price$170/mo$149/mo
Medication typesnad-injectionnad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue
Best for
Overall ranking#13#17
Real monthly cost (25%)7.05.5
Prescriber & follow-up (30%)7.05.5
What they can prescribe (20%)5.58.5
What they disclose (25%)7.05.0

Sources: YourEra pricing verified on yourera.com, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

YourEra

Pros

  • + Flat pricing stated outright — same price at every dose, visit and shipping included
  • + LegitScript-certified, an external check no other clinic in this set carries
  • + Compounded-drug FDA disclosure published in its own words, not buried

Cons

  • Weaker on What they can prescribe (5.5/10)
  • Weaker on Real monthly cost (7.0/10)
  • Weaker on Prescriber & follow-up (7.0/10)

RxSpan MD

Pros

  • + Eight longevity treatments, each with a figure attached
  • + Price is stated to include consult, medication, supplies, shipping and support
  • + Says plainly that a prescription is not guaranteed

Cons

  • Weaker on What they disclose (5.0/10)
  • Weaker on Real monthly cost (5.5/10)
  • Weaker on Prescriber & follow-up (5.5/10)

The bottom line

After scoring all 21 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), YourEra (6.7/10) comes out ahead of RxSpan MD (6.0/10) — but the right choice still depends on what matters most to you.

Choose YourEra if you want this optionfrom $170/mo.

Visit YourEra

Choose RxSpan MD if you want this optionfrom $149/mo.

Visit RxSpan MD

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo — read the review →

Ready to start longevity care?

Our verdict for this matchup is YourEra.

Frequently asked questions

Which is better, YourEra or RxSpan MD?
YourEra scores higher overall (6.7/10 vs 6.0/10) and is our recommended pick for most people. If price is the priority, RxSpan MD starts at $149/mo.
How much does YourEra cost vs RxSpan MD?
YourEra is from $170/mo and RxSpan MD is from $149/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between YourEra and RxSpan MD?
YourEra (6.7/10, #13 of 21) and RxSpan MD (6.0/10, #17 of 21) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does YourEra or RxSpan MD take insurance?
Neither YourEra nor RxSpan MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs YourEraHealthRX vs RxSpan MDMadeMed vs YourEraMadeMed vs RxSpan MDPallas Health vs YourEraPallas Health vs RxSpan MD
Ranked by score

Top picks

HealthRXfrom $161/mo

Best for published pricing

Paid link · ranks 1 of 21 on our methodology either way
Go to HealthRXRead review
MadeMedfrom $169/mo

Best for clinical specificity

Ranks 2 of 21 · no commercial relationship
Read the MadeMed review
Pallas Healthfrom $189/mo

Best for explaining the category

Paid link · ranks 3 of 21 on our methodology either way
Go to Pallas HealthRead review

2 of these earn us a commission if you sign up. Scores and rank are unaffected. How this works →

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.

Top Pick · $161/mo

HealthRX

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$161/mo is a real, ongoing rate on the plan it applies to — our evidence shows no sign it's a promotional rate that rises later.