LMy Longevity Picks

YourEra vs RxSpan MD: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

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Short answer

YourEra wins overall, scoring 6.7/10 vs 6.1/10. Mainly on what they can prescribe and what they disclose. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).

Our pick: YourEra

YourEra wins overall, scoring 6.7/10 vs 6.1/10. If price is your priority, RxSpan MD is cheaper at $150/mo on a prepaid 12-month plan ($249 month to month).

YourEra · from $170/mo with no long-term contract, cancel anytime

Winner
#20 of 31

YourEra

6.7

LegitScript-certified, and its affiliate link lands on a page that never mentions NAD+, the product we ranked it for.

from $170/mo with no long-term contract, cancel anytime

Visit →
#26 of 31

RxSpan MD

6.1

Eight longevity treatments priced, and not one ongoing price.

from $150/mo on a prepaid 12-month plan ($249 month to month)

Visit →

YourEra vs RxSpan MD, side by side

FeatureYourEraRxSpan MD
Our score6.7/106.1/10
Starting price$170/mo with no long-term contract, cancel anytime$150/mo on a prepaid 12-month plan ($249 month to month)
Medication typesnad-injectionnad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue
Best for——
Overall ranking#20#26
Real monthly cost (25%)7.06.0
Prescriber & follow-up (30%)7.05.5
What they can prescribe (20%)5.58.5
What they disclose (25%)7.05.0

Sources: YourEra pricing verified on yourera.com, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

YourEra

Pros

  • + Flat pricing stated outright. Same price at every dose, visit and shipping included
  • + LegitScript-certified, with the public listing on legitscript.com linked from the site
  • + Compounded-drug FDA disclosure published in its own words, not buried

Cons

  • − Weaker on What they can prescribe (5.5/10)
  • − Weaker on Real monthly cost (7.0/10)
  • − Weaker on Prescriber & follow-up (7.0/10)

RxSpan MD

Pros

  • + Eight longevity treatments, each with a figure attached
  • + Price is stated to include consult, medication, supplies, shipping and support
  • + Says plainly that a prescription is not guaranteed

Cons

  • − Weaker on What they disclose (5.0/10)
  • − Weaker on Prescriber & follow-up (5.5/10)
  • − Weaker on Real monthly cost (6.0/10)

The bottom line

After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), YourEra (6.7/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.

Choose YourEra if you want this option. From $170/mo with no long-term contract, cancel anytime.

Visit →

Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).

Visit →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

Ready to start longevity care?

Our verdict for this matchup is YourEra.

YourEra · from $170/mo with no long-term contract, cancel anytimeVisit →
RxSpan MD · from $150/mo on a prepaid 12-month plan ($249 month to month)Visit →
See full rankings

Frequently asked questions

Which is better, YourEra or RxSpan MD?
YourEra scores higher overall (6.7/10 vs 6.1/10) and is our recommended pick for most people. If price is the priority, RxSpan MD starts at $150/mo on a prepaid 12-month plan ($249 month to month).
How much does YourEra cost vs RxSpan MD?
YourEra is from $170/mo with no long-term contract, cancel anytime and RxSpan MD is from $150/mo on a prepaid 12-month plan ($249 month to month). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between YourEra and RxSpan MD?
YourEra (6.7/10, #20 of 31) and RxSpan MD (6.1/10, #26 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does YourEra or RxSpan MD take insurance?
Neither YourEra nor RxSpan MD typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

HealthRX vs YourEra→HealthRX vs RxSpan MD→MadeMed vs YourEra→MadeMed vs RxSpan MD→Ivy Rx vs YourEra→Ivy Rx vs RxSpan MD→
Ranked by score

Top picks

HealthRXfrom $161/mo on a 1-month plan, renewing monthly

Published prices on every product

Paid link · ranks 1 of 31 on our methodology either way
Visit →Read review
MadeMedfrom $169/mo on a 6-month plan billed $1,014

Best for clinical specificity

Ranks 2 of 31 · no commercial relationship
Read the MadeMed review
Ivy RxIvy Rxfrom $175 with no billing period stated

Best named clinical oversight

Ranks 3 of 31 · no commercial relationship
Read the Ivy Rx review

One of these earns us a commission if you sign up. Scores are unaffected; partners are listed first at equal displayed scores. How this works →

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.