Lttl vs He & She MD: Which longevity Clinic Is Better in 2026?
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Short answer
Lttl wins overall, scoring 7.4/10 vs 6.8/10. Mainly on real monthly cost and what they disclose.
Lttl wins overall, scoring 7.4/10 vs 6.8/10.
Lttl · from $99/mo on a 12-month supply, $1,188 billed up front
LLttl
Prices every plan with the amount billed up front and names its four pharmacies, but the review rating on its pages does not match its Trustpilot record and its refund pages contradict each other.
from $99/mo on a 12-month supply, $1,188 billed up front
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He & She MD
Publishes the whole ladder and the dose. Then quotes a different annual price on its own two longevity pages.
from $229/mo on a monthly plan ($139/mo on the annual plan)
Read ReviewLttl vs He & She MD, side by side
| Feature | Lttl | He & She MD |
|---|---|---|
| Our score | 7.4/10 | 6.8/10 |
| Starting price | $99/mo on a 12-month supply, $1,188 billed up front | $229/mo on a monthly plan ($139/mo on the annual plan) |
| Medication types | nad-injection, nad-nasal-spray, nad-liposomal, sermorelin-injection, glutathione-injection, methylene-blue, mic-b12 | nad-injection, nad-nasal-spray, nad-cream, sermorelin-injection, glutathione-injection, glutathione-cream |
| Best for | — | — |
| Overall ranking | #8 | #19 |
| Real monthly cost (25%) | 8.0 | 7.0 |
| Prescriber & follow-up (30%) | 6.5 | 6.0 |
| What they can prescribe (20%) | 8.5 | 8.5 |
| What they disclose (25%) | 7.0 | 6.0 |
Sources: Lttl pricing verified on lttl.com, He & She MD pricing verified on heandshemd.com
Pros & cons
Lttl
Pros
- + Every plan priced with the amount charged: NAD+ $149 a month month to month, $417 a quarter, $774 for 6 months or $1,188 for 12 months
- + Names its four partner pharmacies with addresses in its Terms, each with no FDA warning letter on file
- + Three NAD+ forms (injection, nasal spray, liposomal oral liquid) plus sermorelin, glutathione and methylene blue, at one price for every dose
Cons
- − Not available in 1 state
- − Weaker on Prescriber & follow-up (6.5/10)
- − Weaker on What they disclose (7.0/10)
He & She MD
Pros
- + Full commitment ladder published before intake, all four tiers
- + NAD+ dose published (1000 mg)
- + Six longevity products across injection, cream and nasal spray
Cons
- − Weaker on Prescriber & follow-up (6.0/10)
- − Weaker on What they disclose (6.0/10)
- − Weaker on Real monthly cost (7.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Lttl (7.4/10) comes out ahead of He & She MD (6.8/10). But the right choice still depends on what matters most to you.
Choose Lttl if you want this option. From $99/mo on a 12-month supply, $1,188 billed up front.
Visit →Choose He & She MD if you want this option. From $229/mo on a monthly plan ($139/mo on the annual plan).
Read Review →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is Lttl.
Frequently asked questions
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.