Lttl vs RxSpan MD: Which longevity Clinic Is Better in 2026?
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Short answer
Lttl wins overall, scoring 7.4/10 vs 6.1/10. Mainly on real monthly cost and what they disclose.
Lttl wins overall, scoring 7.4/10 vs 6.1/10.
Lttl · from $99/mo on a 12-month supply, $1,188 billed up front
LLttl
Prices every plan with the amount billed up front and names its four pharmacies, but the review rating on its pages does not match its Trustpilot record and its refund pages contradict each other.
from $99/mo on a 12-month supply, $1,188 billed up front
Visit →
Eight longevity treatments priced, and not one ongoing price.
from $150/mo on a prepaid 12-month plan ($249 month to month)
Visit →Lttl vs RxSpan MD, side by side
| Feature | Lttl | RxSpan MD |
|---|---|---|
| Our score | 7.4/10 | 6.1/10 |
| Starting price | $99/mo on a 12-month supply, $1,188 billed up front | $150/mo on a prepaid 12-month plan ($249 month to month) |
| Medication types | nad-injection, nad-nasal-spray, nad-liposomal, sermorelin-injection, glutathione-injection, methylene-blue, mic-b12 | nad-injection, nad-nasal-spray, nad-tablet, sermorelin-odt, glutathione, ghk-cu, mic-b12, methylene-blue |
| Best for | — | — |
| Overall ranking | #8 | #26 |
| Real monthly cost (25%) | 8.0 | 6.0 |
| Prescriber & follow-up (30%) | 6.5 | 5.5 |
| What they can prescribe (20%) | 8.5 | 8.5 |
| What they disclose (25%) | 7.0 | 5.0 |
Sources: Lttl pricing verified on lttl.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
Lttl
Pros
- + Every plan priced with the amount charged: NAD+ $149 a month month to month, $417 a quarter, $774 for 6 months or $1,188 for 12 months
- + Names its four partner pharmacies with addresses in its Terms, each with no FDA warning letter on file
- + Three NAD+ forms (injection, nasal spray, liposomal oral liquid) plus sermorelin, glutathione and methylene blue, at one price for every dose
Cons
- − Not available in 1 state
- − Weaker on Prescriber & follow-up (6.5/10)
- − Weaker on What they disclose (7.0/10)
RxSpan MD
Pros
- + Eight longevity treatments, each with a figure attached
- + Price is stated to include consult, medication, supplies, shipping and support
- + Says plainly that a prescription is not guaranteed
Cons
- − Weaker on What they disclose (5.0/10)
- − Weaker on Prescriber & follow-up (5.5/10)
- − Weaker on Real monthly cost (6.0/10)
The bottom line
After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Lttl (7.4/10) comes out ahead of RxSpan MD (6.1/10). But the right choice still depends on what matters most to you.
Choose Lttl if you want this option. From $99/mo on a 12-month supply, $1,188 billed up front.
Visit →Choose RxSpan MD if you want this option. From $150/mo on a prepaid 12-month plan ($249 month to month).
Visit →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →
Ready to start longevity care?
Our verdict for this matchup is Lttl.
Frequently asked questions
Which is better, Lttl or RxSpan MD?
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.