LMy Longevity Picks

Lttl vs System Labs: Which longevity Clinic Is Better in 2026?

31 clinics scoredPrices checked weekly0 paid rankings

Summarize this page with

Short answer

Lttl wins overall, scoring 7.4/10 vs 7.3/10. Mainly on real monthly cost and what they disclose.

Our pick: Lttl

Lttl wins overall, scoring 7.4/10 vs 7.3/10.

Lttl · from $99/mo on a 12-month supply, $1,188 billed up front

Winner
#8 of 31

LLttl

7.4

Prices every plan with the amount billed up front and names its four pharmacies, but the review rating on its pages does not match its Trustpilot record and its refund pages contradict each other.

from $99/mo on a 12-month supply, $1,188 billed up front

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#9 of 31

System LabsSystem Labs

7.3

Six longevity treatments, and a pricing page that gives two different answers.

from $149/mo after an $89 first month, billed monthly

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Lttl vs System Labs, side by side

FeatureLttlSystem Labs
Our score7.4/107.3/10
Starting price$99/mo on a 12-month supply, $1,188 billed up front$149/mo after an $89 first month, billed monthly
Medication typesnad-injection, nad-nasal-spray, nad-liposomal, sermorelin-injection, glutathione-injection, methylene-blue, mic-b12nad-injection, nad-nasal, sermorelin-injection, sermorelin-odt, glutathione-injection, glutathione-nasal
Best for——
Overall ranking#8#9
Real monthly cost (25%)8.06.5
Prescriber & follow-up (30%)6.57.0
What they can prescribe (20%)8.58.0
What they disclose (25%)7.08.0

Sources: Lttl pricing verified on lttl.com, System Labs pricing verified on systemlabs.com

Pros & cons

Lttl

Pros

  • + Every plan priced with the amount charged: NAD+ $149 a month month to month, $417 a quarter, $774 for 6 months or $1,188 for 12 months
  • + Names its four partner pharmacies with addresses in its Terms, each with no FDA warning letter on file
  • + Three NAD+ forms (injection, nasal spray, liposomal oral liquid) plus sermorelin, glutathione and methylene blue, at one price for every dose

Cons

  • − Not available in 1 state
  • − Weaker on Prescriber & follow-up (6.5/10)
  • − Weaker on What they disclose (7.0/10)

System Labs

Pros

    Cons

    • − Weaker on Real monthly cost (6.5/10)
    • − Weaker on Prescriber & follow-up (7.0/10)
    • − Weaker on What they can prescribe (8.0/10)

    The bottom line

    After scoring all 31 clinics on our 4-criterion rubric (real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose), Lttl (7.4/10) comes out ahead of System Labs (7.3/10). But the right choice still depends on what matters most to you.

    Choose Lttl if you want this option. From $99/mo on a 12-month supply, $1,188 billed up front.

    Visit →

    Choose System Labs if you want this option. From $149/mo after an $89 first month, billed monthly.

    Visit →

    Editor's overall pick

    Not sold on either? Our highest-rated clinic overall is HealthRX (8.5/10) from $161/mo on a 1-month plan, renewing monthly. Read the review →

    Ready to start longevity care?

    Our verdict for this matchup is Lttl.

    Lttl · from $99/mo on a 12-month supply, $1,188 billed up frontVisit →
    System Labs · from $149/mo after an $89 first month, billed monthlyVisit →
    See full rankings

    Frequently asked questions

    Which is better, Lttl or System Labs?
    Lttl scores higher overall (7.4/10 vs 7.3/10) and is our recommended pick for most people. Lttl also has the lower starting price at $99/mo on a 12-month supply, $1,188 billed up front.
    How much does Lttl cost vs System Labs?
    Lttl is from $99/mo on a 12-month supply, $1,188 billed up front and System Labs is from $149/mo after an $89 first month, billed monthly. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
    What is the difference between Lttl and System Labs?
    Lttl (7.4/10, #8 of 31) and System Labs (7.3/10, #9 of 31) are scored independently across our 4 criteria: real monthly cost, prescriber & follow-up, what they can prescribe and what they disclose. See the detailed score breakdown above for the criterion-by-criterion comparison.
    Does Lttl or System Labs take insurance?
    Neither Lttl nor System Labs typically accepts insurance for longevity treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

    Related comparisons

    HealthRX vs Lttl→HealthRX vs System Labs→MadeMed vs Lttl→MadeMed vs System Labs→Ivy Rx vs Lttl→Ivy Rx vs System Labs→
    Ranked by score

    Top picks

    HealthRXfrom $161/mo on a 1-month plan, renewing monthly

    Published prices on every product

    Paid link · ranks 1 of 31 on our methodology either way
    Visit →Read review
    MadeMedfrom $169/mo on a 6-month plan billed $1,014

    Best for clinical specificity

    Ranks 2 of 31 · no commercial relationship
    Read the MadeMed review
    Ivy RxIvy Rxfrom $175 with no billing period stated

    Best named clinical oversight

    Ranks 3 of 31 · no commercial relationship
    Read the Ivy Rx review

    One of these earns us a commission if you sign up. Scores are unaffected; partners are listed first at equal displayed scores. How this works →

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    How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.